If you'd like to send an email to your subscribers in Hive, except for those that bought a ticket to a specific event, you can exclude these users when choosing who to send the email campaign to.
1) When building a new one-time email campaign, the first step you'll be taken to is the "Choose Recipients" step.
2) To exclude certain ticket purchasers, click View All Filters > Event Data > Purchased Ticket(s) > Purchased Tickets to a Specific Event and search for the ticket purchasers you'd like to exclude from the email send.
3) Toggle the "did" parameter to "didn't".
This will send the email to all of your subscribers, except the users who bought a ticket to the event you're looking to exclude.